Polymarket is leveraging the user base and regulatory standing of fantasy sports leader PrizePix as a gateway to re-enter the U.S. market.
summary
- Polymarket has partnered with fantasy sports leader PrizePix to re-enter the US market through a regulated framework.
- The platform also integrates with DraftKings, establishing itself as the core infrastructure for prediction markets.
According to a prepared statement on Nov. 11, PrizePicks will integrate Polymarket’s event contracts into its platform, giving users access to a new class of predictions for sports, entertainment and cultural events.
The deal comes as Polymarket, long considered a leader in predictive trading, prepares to return to regulated U.S. territory following its acquisition of exchange and clearing house QCEX earlier this year.
“PrizePicks is building one of the most exciting sports communities in the country, and we’re thrilled to be able to help bring prediction markets to that world,” said Polymarket CEO Shayne Coplan. “As we prepare to return to the United States, this partnership demonstrates how prediction markets can strengthen fandom while setting a new standard for interactive and regulated sports participation.”
Prediction markets become mainstream
According to Bloomberg, Polymarket is preparing to return to the US later this month, marking its first regulated entry into the country since it began blocking US users in 2022 as part of a settlement with the CFTC.
The New York-based company’s partnership with PrizePicks gives it an immediate foothold among the millions of active fantasy sports users in the U.S. while easing regulatory friction through an already licensed operating company.
It’s worth noting that the company doesn’t stop at PrizePicks. Polymarket is also preparing to serve as the designated clearing house for DraftKings’ future prediction products, according to comments from DraftKings CEO Jason Robbins during DraftKings’ latest earnings call.
This dual approach by two leading companies signals a deliberate strategy to position Polymarket as a wholesale provider to retail giants and an essential infrastructure layer powering prediction markets across the sector.
This aggressive expansion comes in the midst of a period of tremendous growth for the platform. Polymarket claims that a projected volume of billions of dollars was traded on its platform in 2025 alone. This activity has attracted significant institutional investors, including a strategic investment of up to $2 billion from Intercontinental Exchange, the parent company of the New York Stock Exchange.
The timing of this expansion is no coincidence. The prediction sector is in the midst of a widespread boom, with exchanges and social platforms rushing to capture retail demand for event-based speculation.
For example, Trump Media plans to launch “Truth Prediction,” a regulated prediction platform integrated into its Truth social network. Powered by Crypto.com’s CFTC-registered derivatives exchange, this feature allows users to trade contracts related to elections, economic data, and sports outcomes.

